A paper published online Friday in the New England Journal of Medicine , last Friday.

  1. Most of the patient cohort hospitalized in China for COVID-19 did not initially have fever, and many had no radiologic abnormalities...
  2. Patients' median age was 47, and 42% were women.
  3. Just under one-quarter had a preexisting condition, such as hypertension or COPD.
  4. Most patients were classified as having non-severe disease, and the authors noted those with severe disease were older than the non-severe patients by a median of 7 years.
  5. Overall, about 5% were admitted to the ICU, 2.3% required mechanical ventilation, and 1.4% died.
  6. Cough was the most common symptom, with over two-thirds presenting with cough upon admission. Interestingly, only about 40% presented with fever, though nearly all developed fever while hospitalized.
  7. The authors also noted that about 16% of patients developed "severe illness" after admission to the hospital.
  8. Over 80% of patients had lymphocytopenia present at admission, and most had elevated levels of C-reactive protein.
  9. Researchers reported a median incubation period of 4 days.
  10. While ground-glass opacity was the most common finding on chest CT imaging, they added that in 18% of non-severe cases, no radiographic or CT abnormality was found.
  11. Around 60% of patients received intravenous antibiotics, while about 35% received oseltamivir therapy. About 40% of patients required oxygen therapy.
  12. Patients stayed in the hospital for a median of 12 days, during which time most received a diagnosis of pneumonia.

New England Journal of Medicine

Source Reference: Guan W, et al "Clinical Characteristics of Coronavirus Disease 2019 in China" Nhttps://www.nejm.org/doi/full/10.1056/NEJMoa2002032

https://www.nejm.org/doi/full/10.1056/NEJMoa2002032

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