A paper published online Friday in the New England Journal of Medicine , last Friday.
- Most of the patient cohort hospitalized in China for COVID-19 did not initially have fever, and many had no radiologic abnormalities...
- Patients' median age was 47, and 42% were women.
- Just under one-quarter had a preexisting condition, such as hypertension or COPD.
- Most patients were classified as having non-severe disease, and the authors noted those with severe disease were older than the non-severe patients by a median of 7 years.
- Overall, about 5% were admitted to the ICU, 2.3% required mechanical ventilation, and 1.4% died.
- Cough was the most common symptom, with over two-thirds presenting with cough upon admission. Interestingly, only about 40% presented with fever, though nearly all developed fever while hospitalized.
- The authors also noted that about 16% of patients developed "severe illness" after admission to the hospital.
- Over 80% of patients had lymphocytopenia present at admission, and most had elevated levels of C-reactive protein.
- Researchers reported a median incubation period of 4 days.
- While ground-glass opacity was the most common finding on chest CT imaging, they added that in 18% of non-severe cases, no radiographic or CT abnormality was found.
- Around 60% of patients received intravenous antibiotics, while about 35% received oseltamivir therapy. About 40% of patients required oxygen therapy.
- Patients stayed in the hospital for a median of 12 days, during which time most received a diagnosis of pneumonia.
New England Journal of Medicine
Source Reference: Guan W, et al "Clinical Characteristics of Coronavirus Disease 2019 in China" Nhttps://www.nejm.org/doi/full/10.1056/NEJMoa2002032