Castle Journal

Castle Journal

Scientists have discovered how to make old human cells young again through rejuvenation. It’s an exciting discovery that could change the way humans age.

Researchers at the University of Exeter and University of Brighton found they could rejuvenate senescent cells, cells that had stopped their natural growth cycle,causing them to start to divide again. The experiment found they not only look younger, but also behave like younger cells.


“When I saw some of the cells in the culture dish rejuvenating I couldn't believe it. These old cells were looking like young cells. It was like magic,” researcher Dr. Eva Latorre said“I repeated the experiments several times and in each case the cells rejuvenated. I am very excited by the implications and potential for this research.

The research builds on earlier findings that showed ‘splicing factor’ genes switch off as humans age. Scientists found a way to restart the splicing through chemicals.

According to the researchers, this could change the way we age, with the hope that humans will experience less of the degeneration that comes with aging. Older people are more likely to have strokes, heart disease and other illnesses, but with cell rejuvenation, this could be decreased.

This demonstrates that when you treat old cells with molecules that restore the levels of the splicing factors, the cells regain some features of youth,” team leader Professor Lorna Harries said.  They are able to grow, and their telomeres - the caps on the ends of the chromosomes that shorten as we age -  are now longer, as they are in young cells. Far more research is needed now, to establish the true potential for these sort [sic] of approaches to address the degenerative effects of ageing. ”

MEXICO CITY (Sputnik) -

 

    Ecuadorian Foreign Minister Jose Valencia suggested that WikiLeaks founder Julian Assange, who has found shelter at Ecuador’s embassy in London, should surrender to the UK authorities.

The whistleblower has been living in the Ecuadorian embassy since 2012. The UK authorities have maintained a warrant for Assange's arrest, issued after he breached bail conditions linked to an investigation in Sweden. The Swedish authorities have since dropped their investigation. Assange is fearing potential extradition to the United States, as WikiLeaks has published a number of classified documents, allegedly leaked from US government agencies.

The foreign minister reiterated calls on Assange to comply with a protocol for his stay at the embassy.

Last year, the Ecuadorian authorities introduced the home rules, restricting Assange’s visits and communications. The whistleblower’s lawyers challenged the decision in the court saying the restrictions violated Assange’s rights. Moreover, Assange has suggested that he has been spied on in the embassy. However, Assange's appeal was dismissed by an Ecuadorian court in December.

BEIJING, Jan. 10 (Xinhua) --

Xi Jinping, general secretary of the Central Committee of the Communist Party of China (CPC) and Chinese president, on Tuesday held talks with Kim Jong Un, chairman of the Workers' Party of Korea (WPK) and chairman of the State Affairs Commission of the Democratic People's Republic of Korea (DPRK), who arrived in Beijing on the same day for a visit to China.

In a cordial and friendly atmosphere, the two leaders had an in-depth exchange of views on China-DPRK relations and issues of common concern, and reached important consensus.

The two sides agreed to make joint efforts to push for continuous new development of China-DPRK relations in the new era, constantly advance the political settlement process of the Korean Peninsula issue, bring more benefits to people of the two countries, and make positive contribution to peace, stability, prosperity and development of the region and the world.

Xi pointed out that Comrade Chairman's visit to China at the beginning of 2019, which marks the 70th anniversary of the establishment of China-DPRK diplomatic relationship, fully embodied the great importance Comrade Chairman attaches to the two countries' traditional friendship and Comrade Chairman's friendship with the CPC and the Chinese people.

"I highly appreciate it, and, on behalf of the CPC, the Chinese government and the Chinese people, extend sincere festival greetings to the WPK and the government and the people of the DPRK, "Xi said.

Xi stressed that with concerted efforts of both sides, the China-DPRK relations opened a new historic chapter in 2018. The two sides, with concrete actions, have demonstrated the strong vitality of the China-DPRK friendship and displayed the resolute determination of the two countries to jointly advance the political settlement of the Korean Peninsula issue. This year marks the 70th anniversary of the establishment of the China-DPRK relationship and bears great significance to the efforts of building on past successes to further advance bilateral relationship.

"I am willing to work with Comrade Chairman to make sound efforts to guide the future development of China-DPRK relationship," Xi said.

He said the two sides should maintain high-level exchanges, strengthen strategic communication, deepen friendly exchanges and cooperation, and promote the long-term, healthy and stable development of China-DPRK relations.

Kim said he was grateful to General Secretary Xi for taking time from a busy schedule at the beginning of the year to receive the DPRK delegation. He extended festival greetings to the CPC, the Chinese government and the Chinese people on behalf the WPK, the government and the people of the DPRK.

"Under the utmost care of Comrade General Secretary, the DPRK-China relations last year were elevated to a new height and a new chapter was written," he said.

Kim said with this visit, he hoped to take the opportunity of the 70th anniversary of the establishment of diplomatic relations between the two countries to conduct deep exchanges of views with Comrade General Secretary on consolidating the DPRK-China traditional friendship and stepping up the DPRK-China exchanges and cooperation, and to push for the DPRK-China friendly ties to be consolidated and improved with each passing day.

On the situation of the Korean Peninsula, Xi spoke highly of the positive measures taken by the DPRK side to maintain peace and stability and promote the realization of denuclearization on the peninsula.

He said major progress was made in the process of a political solution to the Korean Peninsula issue last year with joint efforts of China, the DPRK and relevant parties.

Noting that a general trend of peaceful dialogue on the peninsula has taken shape, Xi said it has become the international community's common expectation and consensus for the dialogue to continue and yield results. The political settlement of the Peninsula issue faces a rare historic opportunity.

China supports the DPRK's continued adherence to the direction of denuclearization on the peninsula, supports the continuous improvement of inter-Korean relations, supports the DPRK and the United States holding summits and achieving results, and supports relevant parties resolving their respective legitimate concerns through dialogue, Xi said.

China hopes that the DPRK and the United States will meet each other halfway, Xi said, adding China stands ready to work with the DPRK and relevant parties to play a positive and constructive role in maintaining peace and stability and realizing denuclearization on the peninsula and lasting peace and stability in the region.

Kim said the Korean Peninsula situation has been easing since last year, and China's important role in this process is obvious to all. He said the DPRK side highly and sincerely appreciates the Chinese efforts.

The DPRK will continue sticking to the stance of denuclearization and resolving the Korean Peninsula issue through dialogue and consultation, and make efforts for the second summit between DPRK and U.S. leaders to achieve results that will be welcomed by the international community, Kim said.

Kim said he hoped that relevant parties will attach importance to and positively respond to the DPRK's legitimate concerns, and jointly push for a comprehensive resolution of the Korean Peninsula issue.

The two sides informed each other of their respective countries' situations. Xi said this year marks the 70th anniversary of the founding of New China. In the past seven decades, the CPC has led the Chinese people in achieving a historic leap: they have stood up, grown rich, and are becoming strong. The CPC has the resolve and confidence to unite and lead people of all ethnic groups in China to overcome all difficulties, obstacles, risks and challenges and forge ahead towards the realization of the two centenary goals and the Chinese Dream of national rejuvenation.

Xi said positive results have been achieved since the WPK implemented the new strategic line in the past year, demonstrating the WPK and DPRK people's strong will of loving peace and pursuing development, and receiving wholehearted support from the DPRK people and positive comments from the international community. The Chinese side firmly supports Comrade Chairman in leading the WPK and the people to implement the new strategic line and focus on developing economy and improving people's wellbeing.

"We believe that the DPRK people will surely and constantly make new and greater achievements in the cause of socialist construction, "Xi said.

Kim said that having visited China four times in less than a year, he was deeply impressed by the achievements made in China's economic and social development as well as the Chinese people's spirit and character of striving for the country's prosperity.

The DPRK side considers China's development experience most valuable and hopes for more trips to China for study and exchanges, he said.

Kim said he believes that under the leadership of the CPC with Comrade General Secretary at the core, the Chinese people will continuously make fresh great achievements on the road of socialism with Chinese characteristics in the new era, and successfully realize the two centenary goals and the Chinese Dream of national rejuvenation.

The WPK will lead the DPRK people to continue their great efforts to implement the DPRK's new strategic line and create a favorable external environment for this endeavor, Kim said.

Prior to the talks, Xi held a welcome ceremony for Kim at the Great Hall of the People.

After the talks, Xi and his wife Peng Liyuan hosted a welcome banquet for Kim and his wife Ri Sol Ju, and they watched an art performance together.

On Wednesday morning, Xi met with Kim at Beijing Hotel. Xi spoke positively of the significance of Kim's visit to China this time and looked back on the history of friendly exchanges between China and the DPRK. Xi said China is willing to make joint efforts with the DPRK to safeguard, consolidate and develop relations between the two parties and two countries, jointly write a new chapter of development of relations between the two countries, and jointly make new contributions to regional peace, stability, development and prosperity.

Kim said the DPRK highly values the sound momentum of continuous development of DPRK-China relations, and is willing to work with China to earnestly implement the important consensus reached between the two sides and continue writing a more glorious future of friendship from a new starting point.

Peng Liyuan and Ri Sol Ju attended the meeting.

After the meeting, Xi and his wife held a luncheon for Kim and his wife.

On Wednesday, Kim also visited a Tong Ren Tang pharmaceutical plant in Yizhuang, Beijing, where he inspected relevant processing and production lines of traditional Chinese medicine that use traditional and modern techniques.

Related activities were also attended by Wang Huning, member of the Standing Committee of the Political Bureau of the CPC Central Committee and member of the Secretariat of the CPC Central Committee; Ding Xuexiang, member of the Political Bureau of the CPC Central Committee, member of the Secretariat of the CPC Central Committee and director of the General Office of the CPC Central Committee; Yang Jiechi, member of the Political Bureau of the CPC Central Committee and director of the Office of the Foreign Affairs Commission of the CPC Central Committee; Guo Shengkun, member of the Political Bureau of the CPC Central Committee, member of the Secretariat of the CPC Central Committee and head of the Commission for Political and Legal Affairs of the CPC Central Committee; Huang Kunming, member of the Political Bureau of the CPC Central Committee, member of the Secretariat of the CPC Central Committee and head of the Publicity Department of the CPC Central Committee; Cai Qi, member of the Political Bureau of the CPC Central Committee and secretary of the CPC Beijing Municipal Committee; and State Councilor and Foreign Minister Wang Yi.

Ri Su Yong, member of the Political Bureau of the WPK Central Committee, vice-chairman of the WPK Central Committee and director of the International Department; Kim Yong Chol, member of the Political Bureau of the WPK Central Committee, vice-chairman of the WPK Central Committee and director of the United Front Department; Pak Thae Song, member of the Political Bureau of the WPK Central Committee and vice-chairman of the WPK Central Committee; Ri Yong Ho, member of the Political Bureau of the WPK Central Committee and foreign minister; No Kwang Chol, alternate member of the Political Bureau of the WPK Central Committee and minister of People's Armed Forces; and Kim Yo Jong, alternate member of the Political Bureau of the WPK Central Committee and first vice director of the Propaganda and Agitation Department, accompanied Kim Jong Un on his China tour and attended related activities.

Source Copied | (Xinhua) 

  Jerusalem;

Editing by\Abeer Almadawy

  According to Israeli media reported that the Israeli Military police has arrested 5 IDF "Israel Defense Force " for a reporter said, they tortured 2 detains of palestinians.

The soldiers are an Israel Defense Force platoon commander and four troops serving in his unit ,All of them are members of the Netzah Yehuda Battalion, a unit designed for Orthodox Jews to be able to serve in the defense force and stay true to their religious convictions.

The Jerusalem Post pointed that the battalion receives a range of recruits, from ultra-Orthodox Israelis to immigrants and would-be settlers.

wHILE the military court hearing did not uncover when the alleged beating took place, though the military said the Palestinians were detained in the Ramallah area, a Palestinian city in the West Bank just north of Jerusalem. It's not clear what charges the five are being tried for.

The court lengthened the detention of the officer until Sunday. The four soldiers will stay locked up until next Tuesday.

SOURCE|SPUTINK 

Cairo

Written by: Ahmed Rami

Mr. president Abdul Fattah Al-Sisi received today Mr. Mike Pompeo, Secretary of State of the United States of America, in the presence of Foreign Minister Sameh Shukri and Mr. Abbas Kamel, Head of General Intelligence.

Ambassador Bassam Radhi, Spokesperson for the Presidency stated that President Al sisi  welcomed the US Secretary of State. He conveyed his greetings to President Donald Trump and stressed Egypt's keenness to strengthen bilateral cooperation between the two countries and deepen their strategic partnership, Stability in the Middle East, as well as the aspiration to maximize coordination and consultation with the United States on various political and security issues of common concern.

On the other hand, Pompeo conveyed the greetings of the American President Donald Trump to the Egyptian President, Abdul Fattah AlSisi , on the simultaneous inauguration of Al Fattah Al Alim Mosque and the Cathedral of the Birth of Christ, which reflects Egyptian efforts to consolidate the principles of brotherhood and coexistence. In Egypt, which was reflected in the remarkable development of the progress that  witnessed by the country.

The US Secretary of State also stressed his country's interest in strengthening strategic relations with Egypt, as well as intensifying coordination and joint consultation on Middle East issues, in light of the political weight and leadership of Egypt in its regional environment.

The Spokesman pointed out that the meeting touched upon the file of combating terrorism and extremist ideology. In this context, the Egyptian president stressed the determination of the Egyptian government and people to continue their efforts to confront and defeat this scourge and undermine its security and intellectual danger. The United States on all sides to support those efforts.

For his part, the US Secretary of State praised the success of Egypt's resolute and decisive efforts in this regard during the past period, expressing his country's support for these efforts, stressing that Egypt is a central partner in addressing the challenge of cross-border terrorism.

Ambassador Bassam Radhi added that the meeting also discussed a number of regional issues, especially the developments in Libya, Syria and Yemen, and the efforts to reach a political settlement to these crises, thus preserving their territorial integrity and the integrity of their national institutions. Areas of influence for external forces, as well as provide a security basis to combat terrorist organizations and the siege of elements to prevent their transfer to other countries in the region.

The two sides also reviewed the latest developments in the Palestinian issue and means of reviving the peace process. The Egyptian president affirmed Egypt's firm stance in this regard to reach a just and comprehensive solution that guarantees the rights of the Palestinian people and the establishment of an independent state according to the international references, expressing Egypt's keenness to cooperate with the United States. Palestinian-Israeli negotiations process.

 

Thursday, 10 January 2019 01:02

US citizen was arrested in Iran

Washington

The New York Times reported on Monday that US citizen Michael White, a 46-year-old U.S. Navy veteran, was arrested while visiting Iran and had been held since July on unspecified charges.

Iran had not confirmed the arrest before the state news agency IRNA carried a statement by foreign ministry spokesman Bahram Qassemi on Wednesday, which did not specify when it had happened or what crime he was accused of.

Qassemi said Iran had informed the U.S. government about White's arrest within days of when he was taken into custody and denied that White had been poorly treated.

"These sorts of reports are lies and improper and are seriously rejected," IRNA quoted Qassemi as saying.

White's case is going through the legal process and officials will make a statement at the appropriate time, he added.

The case is likely to further worsen relations with the United States. President Donald Trump withdrew from an international agreement Iran's nuclear programme and re-imposed sanctions last year that hit the Iranian economy hard.

Several Americans have been detained in Iran in recent years and Trump warned in 2017 that Tehran would face "new and serious consequences" unless all unjustly held U.S. citizens were freed.

White's mother, Joanne, told the New York Times her son had visited Iran "five or six times" to meet his Iranian girlfriend.

She reported her son's disappearance after he failed to return in July but learned from the State Department only three weeks ago that he was being held in Iran.

London-based news website IranWire, which first reported White's arrest, quoted a former detainee, Ivar Farhadi, as saying he had been held at the same prison, Vakilabad, in Mashhad, northeastern Iran.

Farhadi told IranWire White's life was in danger because he was being kept in a prison with dangerous criminals.

 

Joanne White told the New York Times her son, a California resident, suffers acute asthma and had had chemotherapy and radiation treatment for a neck tumour.

Reuters

London: AAP

 

An English cricketer whose Australian teammate allegedly raped a sleeping woman has told jurors the accused is still his best friend.

England Lions and former Worcestershire batsman Joe Clarke told a court he had consensual sex with the woman before leaving her in a bedroom to be sick in a bathroom, where he fell asleep.

Clarke, who was arrested but not charged with any offence, told Worcester Crown Court the next thing he remembered was the woman waking him and claiming she had been raped by his friend Alex Hepburn.

Perth-born Hepburn, an all-rounder with English county Worcestershire, denies rape, claiming the woman opened her eyes and kissed him at the start of a 20-minute sexual encounter.

 

The woman, who cannot be identified, broke down in the witness box on Tuesday after being cross-examined about details of the alleged attack.

Giving evidence on Tuesday, Clarke, who now plays for Nottinghamshire, claimed the woman contacted him about four months after the incident and told him she wanted to drop the case.

Recalling the night of the alleged rape in April 2017, Clarke told a jury of eight women and four men that he left a bedroom to be sick after drinking Guinness, vodka and other spirits during a night out.

"I didn't want to be sick in front of her so I went to the bathroom," the 22-year-old told the court.

 

Clarke said the next thing he was aware of was the woman waking him up and saying: "Your housemate has just slept with me. Alex has raped me."

Asked by prosecutor Miranda Moore QC what his reaction had been, Clarke added: "I was very shocked. I put my head in my hands and just questioned it.

"It was a massive shock. I just kept saying 'What?' She shook me and woke me and just said 'Alex has raped me'."

Clarke, the court was told, then asked Hepburn about the claims and "he just said no and shook his head".

Answering questions from defence counsel Michelle Heeley QC, Clarke said the woman had sought him out in August or September 2017 and seemed eager to speak with him.

 

"I told her I didn't want to speak to her," he said.

"She said that she didn't want any of this to happen, to which I said 'if you didn't want any of this to happen, it wouldn't still be going on'.

"She said 'I wanted to drop it but they won't let me'."

The court has heard claims that both Hepburn and Clarke were involved in a sexual conquest "game" after setting up a "stat chat" page on WhatsApp to keep a record of sex with women.

Heeley described the "game" as "basically a contest as to who could sleep with the most women".

 

In her last question to Clarke, Heeley asked: "Is Alex still your best friend?"

Clarke responded: "Yes."

The defence case is due to start on Wednesday.

Hepburn, 23, has pleaded not guilty to two counts of rape.

sOURCE| AAP

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